Elder Ephraim
of Arizona.

Ioannis Moraitis was born on June 24, 1928 (some sources record 1927), in Volos, Greece, on the feast day of the Nativity of St. John the Baptist - a coincidence noted by many who knew him as prophetic of his vocation. His parents were Demetrios and Victoria Moraitis. The family lived in material poverty, and young Ioannis helped his father with his labors; yet he was shaped above all by the profound piety of his mother Victoria, whom he would later tonsure as a nun with the monastic name Theophano. From the age of fourteen, he felt an irresistible longing for the monastic life, but waited patiently for a blessing to depart.

At the age of nineteen, Ioannis left Volos for the Holy Mountain of Athos, arriving at the skete of St. Anna on September 26, 1947. According to accounts he later recorded in his writings, an extraordinary sign preceded his arrival: St. John the Baptist appeared to Elder Joseph the Hesychast, indicating that a young man named "little Ioannis" was being entrusted to his care. Elder Joseph's disciple Arsenios met the young man at the pier and confirmed this heavenly message, saying that Elder Joseph had learned of his arrival from "the Fair Forerunner." Thus Ioannis entered the brotherhood of Elder Joseph the Hesychast at the keliya (hut) of the cave of the Forerunner in New Skete, Mount Athos.

On July 13, 1948, Ioannis was tonsured a monk and given the name Ephraim. He was subsequently ordained a deacon and then a priest, accepting these dignities in humble obedience to his elder's direction. Life under Elder Joseph was exceedingly austere: the brotherhood practiced unceasing prayer - with emphasis on the Jesus Prayer - rigorous fasting, all-night vigils, and absolute obedience to the elder. Elder Ephraim later testified that his twelve years under Saint Joseph were the bedrock of everything that followed in his ministry. The brotherhood's rule, grounded in the patristic hesychast tradition, would later be transplanted to every monastery he founded.

When Saint Joseph the Hesychast reposed on August 15, 1959, Elder Ephraim became the geronda of the brotherhood at the hut of the Annunciation of the Theotokos in New Skete. The brotherhood grew from eight monks to more than forty within a decade, and in 1968 relocated to the skete of Provata. In 1973, the Holy Community of Mount Athos petitioned Elder Ephraim to move his brotherhood to the Monastery of Philotheou, which was struggling with declining numbers. He accepted, and from October 1, 1973, served as its abbot until 1991. Under his leadership the monastery's brotherhood grew rapidly and its spiritual life was swiftly renewed. The council of the Holy Mountain also entrusted him with reviving three other Athonite monasteries - Xeropotamou, Konstamonitou, and Karakallou - all of which he repopulated with disciples. He was additionally asked to repopulate the Great Lavra but declined. Several monasteries in Greece also came under his spiritual direction, including the Monastery of St. John the Forerunner in Serres and the Monastery of Panagia the Directress in Portaria.

In 1979, Elder Ephraim traveled to Canada for medical treatment, and during his stay he began hearing the confessions of Greek Orthodox faithful throughout North America. He encountered communities long deprived of regular confession, proper fasting, and the hesychast tradition, and was moved with compassion for their spiritual condition. He began returning to North America with increasing frequency, visiting parishes in Toronto, Vancouver, Montreal, and across the United States. Faced ultimately with a warning from the council of the Holy Mountain that he must choose between Athos and America, he prayed intensely and discerned that his vocation lay in the New World. He stepped down as abbot of Philotheou in 1990–1991 and relocated to the United States under the omophorion of the Greek Orthodox Archdiocese of America (Ecumenical Patriarchate).

The first monastery he established in North America was the Convent of the Nativity of the Mother of God in Pittsburgh, Pennsylvania, in 1989. In the summer of 1995, Elder Ephraim arrived in the Sonoran Desert of Arizona with a small group of Athonite monks, settling on an expanse of land near the town of Florence. There was no electricity, no water, and no building materials at the site. He urged the brotherhood not to despair, and within four months the main church dedicated to St. Anthony the Great had been built through donations and volunteer labor. Today, St. Anthony's Greek Orthodox Monastery spans approximately 2,000 acres and is home to around 35 monks; its grounds encompass multiple chapels, olive groves, citrus orchards, and gardens. Altogether, Elder Ephraim founded approximately 17 monasteries in the United States and Canada (some sources record 19), for men and women, spread across New York, Texas, Florida, Washington, South Carolina, Pennsylvania, Illinois, California, Michigan, Montreal, and Toronto.

Elder Ephraim spent his final years in increasing seclusion and prayer at St. Anthony's Monastery. He was widely regarded as a grace-filled confessor and clairvoyant elder, with thousands of spiritual children worldwide among monastics, clergy, and laypeople. He reposed peacefully in the Lord on the evening of December 7, 2019, at approximately 10:00 PM Mountain Standard Time, at the age of 91, at St. Anthony's Greek Orthodox Monastery in Florence, Arizona.

Elder Ephraim is widely venerated throughout the Orthodox Christian world as one of the great elders of the twentieth and twenty-first centuries. He is considered by many to be the first person to establish authentic Athonite-style monasteries on American soil, transforming the spiritual landscape of North American Orthodoxy. His repose is commemorated annually on December 7 with a solemn Divine Liturgy and memorial service at St. Anthony's Monastery and at affiliated communities throughout the continent. Although not yet formally included in the Synaxarion of Saints, many of the faithful invoke his name in prayer, asking for his intercessions.

His tomb is located in the St. Menas Chapel at St. Anthony's Greek Orthodox Monastery in Florence, Arizona. A mosaic depicting scenes from his life has been installed at the entrance of the chapel, with a corresponding mosaic of his spiritual father, Saint Joseph the Hesychast, on the opposite side. Thousands of Orthodox faithful - including hierarchs of multiple jurisdictions, such as the Patriarch of Antioch, who celebrated a Trisagion at his tomb during a 2023 visit - have made pilgrimage to the monastery. Accounts of consolation, healing, and answered prayers at his tomb have been reported widely, though they have not yet been formally investigated by ecclesiastical authority.

Elder Ephraim authored several important works, including Counsels from the Holy Mountain: Selected from the Letters and Homilies of Elder Ephraim (St. Anthony's Greek Orthodox Monastery, Florence, AZ, 1999; ISBN 0966700031) and My Life with Elder Joseph. At the 47th Clergy-Laity Congress of the Greek Orthodox Archdiocese of America in San Diego in July 2024, Archbishop Elpidophoros publicly urged his canonization; as of 2025, the process is underway but he remains not yet formally glorified. Icons of Elder Ephraim are painted and venerated in many countries, and informal hymns and supplicatory canons have been composed in his honor by pious faithful, though no official service texts have been formally adopted by the Church.